By 1997, Khatib joined Sagesse Beirut, signing a three-year contract; which was renewed by 7 more years. During his time alongside veteran Elie Mechantaf and Sagesse financing tycoon Antoine Choueiri, El Khatib would go on to win 7 Lebanese Basketball Cups, two Arab Club Basketball Championship, and three FIBA Asia Champions Cup titles with Sagesse. El Khatib would then be transferred to Sagesse rivals Sporting Al Riyadi Beirut, in which he helped the team to achieve their first ever FIBA Asia Champions Cup in 2011 and thereafter the Lebanese Basketball League title in the 2014/2015 season against Byblos Club.He also played with Champville Club and helped them to grab the Lebanese basketball title in 2012. On November 10, 2016 Fadi El Khatib official signed with Homenetmen Beirut Basketball Club. In 2017, El Khatib started playing for Champville SC.